Gene

Pttg1ip

Species
Rattus norvegicus
Symbol
Pttg1ip
Name
PTTG1 interacting protein
Synonyms
  • LOC365548
  • PBF
Biotype
protein coding gene
Automated Description
Predicted to enable p53 binding activity. Predicted to be involved in protein import into nucleus. Predicted to act upstream of or within negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and positive regulation of protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTTG1IP (PTTG1 interacting protein).
RGD Description
Predicted to enable p53 binding activity. Predicted to be involved in protein import into nucleus. Predicted to act upstream of or within negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and positive regulation of protein ubiquitination. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTTG1IP (PTTG1 interacting protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15191
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
11.032M11.034M11.036M11.038M11.040M11.042M11.044M11.046M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions