Gene

Creb3l2

Species
Rattus norvegicus
Symbol
Creb3l2
Name
cAMP responsive element binding protein 3-like 2
Synonyms
  • cAMP-responsive element-binding protein 3-like protein 2
  • cyclic AMP-responsive element-binding protein 3-like protein 2
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in positive regulation of gene expression; positive regulation of neuron projection development; and response to endoplasmic reticulum stress. Located in chromatin and perinuclear endoplasmic reticulum. Orthologous to human CREB3L2 (cAMP responsive element binding protein 3 like 2).
RGD Description
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in positive regulation of gene expression; positive regulation of neuron projection development; and response to endoplasmic reticulum stress. Located in chromatin and perinuclear endoplasmic reticulum. Orthologous to human CREB3L2 (cAMP responsive element binding protein 3 like 2); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Huntington's disease pathway; prostate cancer pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46004
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
65.92M65.94M65.96M65.98M66.00M66.02M66.04M66.06M66.08M66.10M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions