Gene

Cc2d1a

Species
Rattus norvegicus
Symbol
Cc2d1a
Name
coiled-coil and C2 domain containing 1A
Synonyms
  • coiled-coil and C2 domain-containing protein 1A
  • five prime repressor element under dual repression-binding protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of snRNA transcription by RNA polymerase II; positive regulation of canonical NF-kappaB signal transduction; and regulation of postsynapse assembly. Predicted to act upstream of or within several processes, including apical dendrite arborization; negative regulation of transcription by RNA polymerase II; and regulation of respiratory gaseous exchange by nervous system process. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 3 and intellectual disability. Orthologous to human CC2D1A (coiled-coil and C2 domain containing 1A).
RGD Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of snRNA transcription by RNA polymerase II; positive regulation of canonical NF-kappaB signal transduction; and regulation of postsynapse assembly. Predicted to act upstream of or within several processes, including apical dendrite arborization; negative regulation of transcription by RNA polymerase II; and regulation of respiratory gaseous exchange by nervous system process. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 3 and intellectual disability. Orthologous to human CC2D1A (coiled-coil and C2 domain containing 1A); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; allethrin.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13076
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
24.012M24.014M24.016M24.018M24.020M24.022M24.024M24.026M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions