Gene

Dclre1a

Species
Rattus norvegicus
Symbol
Dclre1a
Name
DNA cross-link repair 1A
Synonyms
  • DNA cross-link repair 1A protein
  • DNA cross-link repair 1A, PSO2 homolog
Biotype
protein coding gene
Automated Description
Predicted to enable 5'-3' DNA exonuclease activity; beta-lactamase activity; and damaged DNA binding activity. Predicted to be involved in double-strand break repair via nonhomologous end joining and interstrand cross-link repair. Predicted to act upstream of or within nucleotide-excision repair. Predicted to be located in fibrillar center and nucleoplasm. Orthologous to human DCLRE1A (DNA cross-link repair 1A).
RGD Description
Predicted to enable 5'-3' DNA exonuclease activity; beta-lactamase activity; and damaged DNA binding activity. Predicted to be involved in double-strand break repair via nonhomologous end joining and interstrand cross-link repair. Predicted to act upstream of or within nucleotide-excision repair. Predicted to be located in fibrillar center and nucleoplasm. Orthologous to human DCLRE1A (DNA cross-link repair 1A); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23240
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
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            255.570M255.572M255.574M255.576M255.578M255.580M255.582M255.584M255.586M255.588M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Dclre1a molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              Dclre1a role
              Dclre1a genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
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