Gene

Tiparp

Species
Rattus norvegicus
Symbol
Tiparp
Name
TCDD-inducible poly(ADP-ribose) polymerase
Synonyms
  • LOC310467
  • RM1
Biotype
protein coding gene
Automated Description
Predicted to enable NAD+-protein poly-ADP-ribosyltransferase activity; NAD+-protein-cysteine ADP-ribosyltransferase activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in response to 2,3,7,8-tetrachlorodibenzodioxine. Predicted to be active in nucleus. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase).
RGD Description
Predicted to enable NAD+-protein poly-ADP-ribosyltransferase activity; NAD+-protein-cysteine ADP-ribosyltransferase activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in response to 2,3,7,8-tetrachlorodibenzodioxine. Predicted to be active in nucleus. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH (+)-schisandrin B; 1,2,3,7,8-Pentachlorodibenzodioxin; 2,2',4,4',5,5'-hexachlorobiphenyl.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45740
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
149.755M149.760M149.765M149.770M149.775M149.780M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions