Predicted to enable several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Predicted to be involved in DNA damage response; heterochromatin formation; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in several cellular components, including chromosomal region; nuclear lumen; and site of DNA damage. Predicted to be part of nucleoplasm; ribonucleoprotein complex; and transcription repressor complex. Orthologous to human CBX5 (chromobox 5).
RGD Description
Predicted to enable several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Predicted to be involved in DNA damage response; heterochromatin formation; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in several cellular components, including chromosomal region; nuclear lumen; and site of DNA damage. Predicted to be part of nucleoplasm; ribonucleoprotein complex; and transcription repressor complex. Orthologous to human CBX5 (chromobox 5); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.