Gene

Cbx5

Species
Rattus norvegicus
Symbol
Cbx5
Name
chromobox 5
Synonyms
  • chromobox homolog 5
  • chromobox homolog 5 (Drosophila HP1a)
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Predicted to be involved in DNA damage response; heterochromatin formation; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in several cellular components, including chromosomal region; nuclear lumen; and site of DNA damage. Predicted to be part of nucleoplasm; ribonucleoprotein complex; and transcription repressor complex. Orthologous to human CBX5 (chromobox 5).
RGD Description
Predicted to enable several functions, including histone deacetylase binding activity; identical protein binding activity; and methylated histone binding activity. Predicted to be involved in DNA damage response; heterochromatin formation; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in several cellular components, including chromosomal region; nuclear lumen; and site of DNA damage. Predicted to be part of nucleoplasm; ribonucleoprotein complex; and transcription repressor complex. Orthologous to human CBX5 (chromobox 5); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22812
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
134.335M134.340M134.345M134.350M134.355M134.360M134.365M134.370M134.375M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions