Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of Rac protein signal transduction; negative regulation of ruffle assembly; and wound healing, spreading of epidermal cells. Predicted to act upstream of or within activation of GTPase activity. Predicted to be located in several cellular components, including adherens junction; cell projection; and cytoskeleton. Predicted to be active in focal adhesion. Orthologous to human ARHGAP24 (Rho GTPase activating protein 24).
RGD Description
Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of Rac protein signal transduction; negative regulation of ruffle assembly; and wound healing, spreading of epidermal cells. Predicted to act upstream of or within activation of GTPase activity. Predicted to be located in several cellular components, including adherens junction; cell projection; and cytoskeleton. Predicted to be active in focal adhesion. Orthologous to human ARHGAP24 (Rho GTPase activating protein 24); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.