Gene

Zc3h12a

Species
Rattus norvegicus
Symbol
Zc3h12a
Name
zinc finger CCCH type containing 12A
Synonyms
  • bifunctional endoribonuclease and deubiquitinase ZC3H12A
  • endoribonuclease ZC3H12A
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including RNA nuclease activity; nucleic acid binding activity; and ribosome binding activity. Predicted to contribute to cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of intracellular signal transduction; and regulation of macromolecule metabolic process. Predicted to be located in several cellular components, including P-body; nucleoplasm; and rough endoplasmic reticulum membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human ZC3H12A (zinc finger CCCH-type containing 12A).
RGD Description
Predicted to enable several functions, including RNA nuclease activity; nucleic acid binding activity; and ribosome binding activity. Predicted to contribute to cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of gene expression; and regulation of intracellular signal transduction. Predicted to be located in several cellular components, including P-body; nucleoplasm; and rough endoplasmic reticulum membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human ZC3H12A (zinc finger CCCH-type containing 12A); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12876
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
137.377M137.378M137.379M137.380M137.381M137.382M137.383M137.384M137.385M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions