Gene

Chd1

Species
Rattus norvegicus
Symbol
Chd1
Name
chromodomain helicase DNA binding protein 1
Synonyms
  • chromodomain-helicase-DNA-binding protein 1
  • LOC308215
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and methylated histone binding activity. Predicted to be involved in nucleosome organization and positive regulation by host of viral transcription. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nuclear chromosome. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and prostate cancer. Orthologous to human CHD1 (chromodomain helicase DNA binding protein 1).
RGD Description
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and methylated histone binding activity. Predicted to be involved in nucleosome organization and positive regulation by host of viral transcription. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nuclear chromosome. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and prostate cancer. Orthologous to human CHD1 (chromodomain helicase DNA binding protein 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45623
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
56.67M56.68M56.69M56.70M56.71M56.72M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions