Gene

Piwil2

Species
Rattus norvegicus
Symbol
Piwil2
Name
piwi-like RNA-mediated gene silencing 2
Synonyms
  • LOC306011
  • piwi like homolog 2
Biotype
protein coding gene
Automated Description
Predicted to enable RNA endonuclease activity; mRNA binding activity; and piRNA binding activity. Predicted to be involved in several processes, including germ-line stem cell population maintenance; negative regulation of circadian rhythm; and regulation of gene expression. Predicted to act upstream of with a positive effect on transposable element silencing by piRNA-mediated heterochromatin formation. Predicted to act upstream of or within positive regulation of meiosis I. Predicted to be located in cytoplasmic ribonucleoprotein granule; dense body; and perinucleolar chromocenter. Predicted to be part of PET complex. Predicted to be active in P granule and nucleus. Orthologous to human PIWIL2 (piwi like RNA-mediated gene silencing 2).
RGD Description
Predicted to enable RNA endonuclease activity; mRNA binding activity; and piRNA binding activity. Predicted to be involved in several processes, including germ-line stem cell population maintenance; negative regulation of circadian rhythm; and regulation of gene expression. Predicted to act upstream of with a positive effect on piRNA-mediated retrotransposon silencing by heterochromatin formation. Predicted to act upstream of or within positive regulation of meiosis I. Predicted to be located in cytoplasmic ribonucleoprotein granule; dense body; and perinucleolar chromocenter. Predicted to be part of PET complex. Predicted to be active in P granule and nucleus. Orthologous to human PIWIL2 (piwi like RNA-mediated gene silencing 2); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; endosulfan.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22891
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
45.44M45.45M45.46M45.47M45.48M45.49M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions