Gene

Psme3

Species
Rattus norvegicus
Symbol
Psme3
Name
proteasome activator subunit 3
Synonyms
  • Ab2-371
  • LOC287716
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; endopeptidase activator activity; and p53 binding activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway and regulation of proteasomal protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of proteasome activator complex. Orthologous to human PSME3 (proteasome activator subunit 3).
RGD Description
Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; endopeptidase activator activity; and p53 binding activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway; regulation of G1/S transition of mitotic cell cycle; and regulation of proteolysis. Predicted to be located in cytosol. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human PSME3 (proteasome activator subunit 3); PARTICIPATES IN antigen processing and presentation pathway; hepatitis C pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10660
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
86.26M86.27M86.28M86.29M86.30M86.31M86.32M86.33M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions