Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; endopeptidase activator activity; and p53 binding activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway and regulation of proteasomal protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of proteasome activator complex. Orthologous to human PSME3 (proteasome activator subunit 3).
RGD Description
Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; endopeptidase activator activity; and p53 binding activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway; regulation of G1/S transition of mitotic cell cycle; and regulation of proteolysis. Predicted to be located in cytosol. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human PSME3 (proteasome activator subunit 3); PARTICIPATES IN antigen processing and presentation pathway; hepatitis C pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.