Gene

Vil1

Species
Rattus norvegicus
Symbol
Vil1
Name
villin 1
Synonyms
  • LOC316521
  • Vil
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; phospholipid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including actin cytoskeleton organization; regulation of actin filament organization; and regulation of cell morphogenesis. Predicted to be located in several cellular components, including brush border; filopodium tip; and ruffle. Orthologous to human VIL1 (villin 1).
RGD Description
Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; phospholipid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including actin cytoskeleton organization; regulation of actin filament organization; and regulation of cell morphogenesis. Predicted to be located in several cellular components, including brush border; filopodium tip; and ruffle. Predicted to be active in actin cytoskeleton; cytoplasm; and lamellipodium. Orthologous to human VIL1 (villin 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11977
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Avil184373597 of 9 
Vill286563456 of 9 
Gsn372863507 of 9 
Scin471066487 of 9 
Svil588740263 of 9 
Flii679745283 of 9 
Capg734059444 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
75.995M76.000M76.005M76.010M76.015M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Vil1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
STXBP5LHomo sapiens
protein
  • affinity chromatography technology
PMID:25002582
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Genetic Interactions