Gene

Lamtor3

Species
Rattus norvegicus
Symbol
Lamtor3
Name
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Synonyms
  • late endosomal/lysosomal adaptor and MAPK and MTOR activator 3
  • LOC362045
Biotype
protein coding gene
Automated Description
Predicted to enable kinase activator activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and protein localization. Predicted to act upstream of or within positive regulation of MAPK cascade and protein localization to cell junction. Predicted to be located in late endosome membrane. Predicted to be part of FNIP-folliculin RagC/D GAP and Ragulator complex. Predicted to be active in late endosome and lysosomal membrane. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3).
RGD Description
Predicted to enable kinase activator activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and protein localization. Predicted to act upstream of or within positive regulation of MAPK cascade and protein localization to cell junction. Predicted to be located in late endosome membrane. Predicted to be part of FNIP-folliculin RagC/D GAP and Ragulator complex. Predicted to be active in late endosome and lysosomal membrane. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; amphetamine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13378
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
226.412M226.414M226.416M226.418M226.420M226.422M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions