Version: 8.0.0
Date: Tue Jan 28 2025
Ccdc186
Rattus norvegicusRGD:1307158
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ccdc186

Species
Rattus norvegicus
Symbol
Ccdc186
Name
coiled-coil domain containing 186
Synonyms
  • coiled-coil domain-containing protein 186
  • LOC361773
Biotype
protein coding gene
Automated Description
Predicted to enable small GTPase binding activity. Predicted to be involved in vesicle cytoskeletal trafficking. Predicted to act upstream of or within insulin secretion involved in cellular response to glucose stimulus and response to bacterium. Predicted to be located in Golgi apparatus. Predicted to be active in trans-Golgi network. Orthologous to human CCDC186 (coiled-coil domain containing 186).
RGD Description
Predicted to act upstream of or within insulin secretion involved in cellular response to glucose stimulus; response to bacterium; and vesicle cytoskeletal trafficking. Predicted to be located in Golgi apparatus. Orthologous to human CCDC186 (coiled-coil domain containing 186); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; mercury dichloride; N,N-diethyl-m-toluamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18911
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Ccdc186 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Ccdc186 role
            Ccdc186 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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