Gene

Nmnat2

Species
Rattus norvegicus
Symbol
Nmnat2
Name
nicotinamide nucleotide adenylyltransferase 2
Synonyms
  • LOC289095
  • naMN adenylyltransferase 1
Biotype
protein coding gene
Automated Description
Predicted to enable nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Involved in NAD biosynthetic process and cellular response to angiotensin. Predicted to be located in several cellular components, including cytosol; late endosome; and trans-Golgi network. Predicted to be active in Golgi apparatus. Biomarker of hypertrophic cardiomyopathy. Orthologous to human NMNAT2 (nicotinamide nucleotide adenylyltransferase 2).
RGD Description
Predicted to enable nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Involved in NAD biosynthetic process and cellular response to angiotensin. Predicted to be located in several cellular components, including cytosol; late endosome; and trans-Golgi network. Predicted to be active in Golgi apparatus. Biomarker of hypertrophic cardiomyopathy. Orthologous to human NMNAT2 (nicotinamide nucleotide adenylyltransferase 2); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bis(2-ethylhexyl) phthalate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12039
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
65.12M65.14M65.16M65.18M65.20M65.22M65.24M65.26M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions