Gene

Atf1

Species
Rattus norvegicus
Symbol
Atf1
Name
activating transcription factor 1
Synonyms
  • Atf-1
  • cyclic AMP-dependent transcription factor ATF-1
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of neuron projection development; positive regulation of nucleobase-containing compound metabolic process; and response to cobalt ion. Part of transcription regulator complex. Biomarker of polycystic kidney disease. Orthologous to human ATF1 (activating transcription factor 1).
RGD Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of neuron projection development; positive regulation of nucleobase-containing compound metabolic process; and response to cobalt ion. Part of transcription regulator complex. Biomarker of polycystic kidney disease. Orthologous to human ATF1 (activating transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45879
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
131.365M131.370M131.375M131.380M131.385M131.390M131.395M131.400M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions