Gene

Dusp19

Species
Rattus norvegicus
Symbol
Dusp19
Name
dual specificity phosphatase 19
Synonyms
  • dual specificity protein phosphatase 19
  • LOC311151
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including phosphoprotein phosphatase activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in negative regulation of JUN kinase activity; positive regulation of JNK cascade; and positive regulation of JUN kinase activity. Predicted to act upstream of or within JNK cascade; negative regulation of MAPK cascade; and protein dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human DUSP19 (dual specificity phosphatase 19).
RGD Description
Predicted to enable several functions, including phosphoprotein phosphatase activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in negative regulation of JUN kinase activity; positive regulation of JNK cascade; and positive regulation of JUN kinase activity. Predicted to act upstream of or within JNK cascade; negative regulation of MAPK cascade; and protein dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human DUSP19 (dual specificity phosphatase 19); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; INTERACTS WITH amphetamine; bisphenol A; cobalt dichloride.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46377
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
65.540M65.542M65.544M65.546M65.548M65.550M65.552M65.554M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions