Gene

Errfi1

Species
Rattus norvegicus
Symbol
Errfi1
Name
ERBB receptor feedback inhibitor 1
Synonyms
  • gene 33
  • gene 33 polypeptide
Biotype
protein coding gene
Automated Description
Enables SH3 domain binding activity; kinase binding activity; and small GTPase binding activity. Involved in several processes, including cellular response to dexamethasone stimulus; cellular response to epidermal growth factor stimulus; and negative regulation of metabolic process. Predicted to be located in cytosol and plasma membrane. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1).
RGD Description
Enables SH3 domain binding activity; kinase binding activity; and small GTPase binding activity. Involved in several processes, including cellular response to dexamethasone stimulus; cellular response to epidermal growth factor stimulus; and negative regulation of macromolecule metabolic process. Predicted to be located in cytosol and plasma membrane. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14254
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensERRFI110 of 10YesYes  
Mus musculusErrfi19 of 9YesYes   
Xenopus tropicaliserrfi19 of 9YesYes   
Danio rerioerrfi1a8 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
161.324M161.326M161.328M161.330M161.332M161.334M161.336M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051340.1:g.161327020A>Cvariant
SNP
  • intron variant
NC_051340.1:g.161330091C>Tvariant
SNP
  • intron variant
NC_051340.1:g.161331177A>Gvariant
SNP
  • intron variant
NC_051340.1:g.161335563C>Tvariant
SNP
  • synonymous variant
NC_051340.1:g.161333371T>Cvariant
SNP
  • intron variant
NC_051340.1:g.161330055G>Avariant
NC_051340.1:g.161325066A>Tvariant
SNP
  • intron variant
NC_051340.1:g.161325110A>Gvariant
SNP
  • intron variant
NC_051340.1:g.161326276G>Avariant
SNP
  • intron variant
NC_051340.1:g.161327914C>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 31 rows
per page

Transgenic Alleles

No data available

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
161.324M161.326M161.328M161.330M161.332M161.334M161.336M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

5 interactor genes based on 5 annotations
Errfi1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Chek1Rattus norvegicus
protein
  • enzymatic study
PMID:23432726
protein
EgfrRattus norvegicus
protein
  • affinity chromatography technology
PMID:23432726
protein
PrkczRattus norvegicus
protein
  • affinity chromatography technology
PMID:23432726
protein
YwhagRattus norvegicus
protein
  • affinity chromatography technology
PMID:23432726
protein
YwhaqRattus norvegicus
protein
  • affinity chromatography technology
PMID:23432726
Showing 1 - 5 of 5 rows
per page

Genetic Interactions