Gene

Celf1

Species
Rattus norvegicus
Symbol
Celf1
Name
CUGBP, Elav-like family member 1
Synonyms
  • bruno-like protein 2
  • CELF-1
Biotype
protein coding gene
Automated Description
Enables mRNA 3'-UTR binding activity. Involved in cellular response to polyamine macromolecule; negative regulation of epithelial cell proliferation; and post-transcriptional regulation of gene expression. Acts upstream of or within positive regulation of gene expression. Predicted to be located in cytoplasmic stress granule and nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human CELF1 (CUGBP Elav-like family member 1).
RGD Description
Enables mRNA 3'-UTR binding activity. Involved in cellular response to polyamine macromolecule; negative regulation of epithelial cell proliferation; and post-transcriptional regulation of gene expression. Acts upstream of or within positive regulation of gene expression. Predicted to be located in cytoplasmic stress granule and nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human CELF1 (CUGBP Elav-like family member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24012
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensCELF110 of 10YesYes  
Mus musculusCelf19 of 9YesYes   
Xenopus tropicaliscelf19 of 9YesYes   
Danio reriocelf19 of 9YesYes   
Drosophila melanogasterbru17 of 9YesYes   
Drosophila melanogasterbru23 of 9NoYes   
Caenorhabditis elegansetr-16 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Celf2155182737 of 9 
Celf3255056406 of 9 
Celf6350057466 of 9 
Celf5451456446 of 9 
Celf4552455416 of 9 
Pabpc2653538232 of 9 
Rbm45752637242 of 9 
Pabpc1l850736222 of 9 
Elavl4950136232 of 9 
Elavl31048137242 of 9 
Elavl21150236222 of 9 
Elavl11248535232 of 9 
Pabpc11349035222 of 9 
Pabpc41447936222 of 9 
Pabpc61549935212 of 9 
Rbm281652135182 of 9 
Rbm31y1745737222 of 9 
Rbms11844837242 of 9 
Pabpc4l1946736202 of 9 
Pabpc52048633202 of 9 
Rbms22141738222 of 9 
Rbms32220643302 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051338.1:g.76976065A>Cvariant
SNP
  • intron variant
NC_051338.1:g.76991484C>Tvariant
SNP
  • intron variant
NC_051338.1:g.76981264G>Avariant
SNP
  • intron variant
NC_051338.1:g.76988320G>Cvariant
SNP
  • intron variant
NC_051338.1:g.76976267T>Cvariant
SNP
  • intron variant
NC_051338.1:g.76967837T>Cvariant
SNP
  • intron variant
NC_051338.1:g.76989336G>Avariant
SNP
  • intron variant
NC_051338.1:g.76990824A>Gvariant
SNP
  • intron variant
NC_051338.1:g.76974004C>Tvariant
SNP
  • intron variant
NC_051338.1:g.76974058A>Cvariant
SNP
  • intron variant
Showing 1 - 10 of 136 rows
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Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
76.93M76.94M76.95M76.96M76.97M76.98M76.99M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Celf1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Prkaa1Rattus norvegicus
protein
  • affinity chromatography technology
PMID:24625528
Showing 1 - 1 of 1 rows
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Genetic Interactions

No data available