Gene

Prcp

Species
Rattus norvegicus
Symbol
Prcp
Name
prolylcarboxypeptidase
Synonyms
  • LOC293118
  • lysosomal Pro-X carboxypeptidase
Biotype
protein coding gene
Automated Description
Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in angiogenesis involved in wound healing; negative regulation of systemic arterial blood pressure; and regulation of blood vessel endothelial cell migration. Predicted to act upstream of or within several processes, including glucose homeostasis; plasma kallikrein-kinin cascade; and regulation of thyroid hormone receptor signaling pathway. Predicted to be located in basal part of cell and lysosome. Biomarker of brain infarction. Orthologous to human PRCP (prolylcarboxypeptidase).
RGD Description
Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in angiogenesis involved in wound healing; negative regulation of systemic arterial blood pressure; and regulation of blood vessel endothelial cell migration. Predicted to act upstream of or within several processes, including glucose homeostasis; plasma kallikrein-kinin cascade; and regulation of thyroid hormone receptor signaling pathway. Predicted to be located in basal part of cell and lysosome. Biomarker of brain infarction. Orthologous to human PRCP (prolylcarboxypeptidase); PARTICIPATES IN kallikrein-kinin cascade pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11010
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensPRCP10 of 10YesYes  
Mus musculusPrcp9 of 9YesYes   
Xenopus tropicalissmyd29 of 9YesYes   
Danio rerioprcp9 of 9YesYes   
Drosophila melanogasterCG24939 of 9YesYes   
Caenorhabditis eleganspcp-59 of 9YesYes   
Caenorhabditis eleganspcp-15 of 9NoYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Dpp7149657424 of 9 
Prss16253343273 of 9 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
146.935M146.940M146.945M146.950M146.955M146.960M146.965M146.970M146.975M146.980M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051336.1:g.146936408C>Tvariant
SNP
  • intron variant
NC_051336.1:g.146946282C>Tvariant
SNP
  • intron variant
NC_051336.1:g.146946820G>Avariant
SNP
  • intron variant
NC_051336.1:g.146947404G>Avariant
SNP
  • intron variant
NC_051336.1:g.146947972A>Tvariant
SNP
  • intron variant
NC_051336.1:g.146941433A>Gvariant
SNP
  • intron variant
NC_051336.1:g.146951162C>Avariant
SNP
  • intron variant
NC_051336.1:g.146951541C>Avariant
SNP
  • intron variant
NC_051336.1:g.146951587T>Cvariant
SNP
  • intron variant
NC_051336.1:g.146952172G>Cvariant
SNP
  • intron variant
Showing 1 - 10 of 274 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
146.935M146.940M146.945M146.950M146.955M146.960M146.965M146.970M146.975M146.980M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available