Version: 8.0.0
Date: Tue Jan 28 2025
Ing5
Rattus norvegicusRGD:1307908
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ing5

Species
Rattus norvegicus
Symbol
Ing5
Name
inhibitor of growth family, member 5
Synonyms
  • inhibitor of growth protein 5
  • LOC363292
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in several processes, including DNA replication-dependent chromatin disassembly; positive regulation of apoptotic signaling pathway; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within negative regulation of fibroblast proliferation and positive regulation of apoptotic process. Predicted to be located in nucleoplasm. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Predicted to be active in nucleus. Orthologous to human ING5 (inhibitor of growth family member 5).
RGD Description
Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in several processes, including DNA replication-dependent chromatin disassembly; positive regulation of apoptotic signaling pathway; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within negative regulation of fibroblast proliferation and positive regulation of apoptotic process. Predicted to be located in nucleoplasm. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Predicted to be active in nucleus. Orthologous to human ING5 (inhibitor of growth family member 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; thioacetamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10333
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Download all Alleles/Variants for all genes of the species

        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            94.328M94.330M94.332M94.334M94.336M94.338M94.340M94.342M94.344M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Ing5 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Ing5 role
              Ing5 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
              Reference
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