Gene

Gmnn

Species
Rattus norvegicus
Symbol
Gmnn
Name
geminin, DNA replication inhibitor
Synonyms
  • geminin
  • LOC291137
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including chromatin binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including DNA replication preinitiation complex assembly; regulation of mitotic cell cycle; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within animal organ morphogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 6. Orthologous to human GMNN (geminin DNA replication inhibitor).
RGD Description
Predicted to enable several functions, including chromatin binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to be involved in several processes, including DNA replication preinitiation complex assembly; regulation of mitotic cell cycle; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within animal organ morphogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 6. Orthologous to human GMNN (geminin DNA replication inhibitor); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13372
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
40.302M40.303M40.304M40.305M40.306M40.307M40.308M40.309M40.310M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions