Gene

Hif1an

Species
Rattus norvegicus
Symbol
Hif1an
Name
hypoxia inducible factor 1 subunit alpha inhibitor
Synonyms
  • hypoxia-inducible factor 1-alpha inhibitor
  • hypoxia-inducible factor 1, alpha subunit inhibitor
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of Notch signaling pathway; positive regulation of myoblast differentiation; and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor).
RGD Description
Predicted to enable several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of Notch signaling pathway; positive regulation of myoblast differentiation; and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12461
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
243.420M243.422M243.424M243.426M243.428M243.430M243.432M243.434M243.436M243.438M243.440M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions