Version: 8.0.0
Date: Tue Jan 28 2025
Tmem126b
Rattus norvegicusRGD:1308371
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Tmem126b

Species
Rattus norvegicus
Symbol
Tmem126b
Name
transmembrane protein 126B
Synonyms
  • complex I assembly factor TMEM126B, mitochondrial
  • hypothetical LOC293114
Biotype
protein coding gene
Automated Description
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within mitochondrion organization and response to food. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 29. Orthologous to human TMEM126B (transmembrane protein 126B).
RGD Description
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within mitochondrion organization and response to food. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 29. Orthologous to human TMEM126B (transmembrane protein 126B); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR16296
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Tmem126b molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Tmem126b role
            Tmem126b genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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