Version: 8.0.0
Date: Tue Jan 28 2025
Ncapg2
Rattus norvegicusRGD:1308406
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ncapg2

Species
Rattus norvegicus
Symbol
Ncapg2
Name
non-SMC condensin II complex, subunit G2
Synonyms
  • condensin-2 complex subunit G2
  • leucine zipper protein 5
Biotype
protein coding gene
Automated Description
Predicted to enable bHLH transcription factor binding activity and methylated histone binding activity. Predicted to be involved in mitotic sister chromatid segregation; positive regulation of chromosome segregation; and positive regulation of chromosome separation. Predicted to act upstream of with a positive effect on erythrocyte differentiation. Predicted to act upstream of with a negative effect on transcription by RNA polymerase II. Predicted to act upstream of or within inner cell mass cell proliferation. Predicted to be located in condensed nuclear chromosome and nuclear speck. Predicted to be part of condensin complex. Predicted to be active in nucleus. Orthologous to human NCAPG2 (non-SMC condensin II complex subunit G2).
RGD Description
Predicted to enable bHLH transcription factor binding activity and methylated histone binding activity. Predicted to be involved in mitotic sister chromatid segregation; positive regulation of chromosome segregation; and positive regulation of chromosome separation. Predicted to act upstream of with a positive effect on erythrocyte differentiation. Predicted to act upstream of with a negative effect on transcription by RNA polymerase II. Predicted to act upstream of or within inner cell mass cell proliferation. Predicted to be located in condensed nuclear chromosome and nuclear speck. Predicted to be part of condensin complex. Predicted to be active in nucleus. Orthologous to human NCAPG2 (non-SMC condensin II complex subunit G2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR16199
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Ncapg2 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Ncapg2 role
            Ncapg2 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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