Gene

Arhgap35

Species
Rattus norvegicus
Symbol
Arhgap35
Name
Rho GTPase activating protein 35
Synonyms
  • GAP-associated protein p190
  • glucocorticoid receptor DNA binding factor 1
Biotype
protein coding gene
Automated Description
Enables GTPase activating protein binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Predicted to be located in actin cytoskeleton; ciliary basal body; and cytoplasm. Predicted to be active in cytosol. Orthologous to human ARHGAP35 (Rho GTPase activating protein 35).
RGD Description
Enables GTPase activating protein binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Predicted to be located in actin cytoskeleton; ciliary basal body; and cytoplasm. Predicted to be active in cytosol. Orthologous to human ARHGAP35 (Rho GTPase activating protein 35); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; platelet-derived growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46005
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
77.22M77.24M77.26M77.28M77.30M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions