Gene

Sox8

Species
Rattus norvegicus
Symbol
Sox8
Name
SRY-box transcription factor 8
Synonyms
  • LOC302993
  • SRY (sex determining region Y)-box 8
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including nervous system development; positive regulation of morphogenesis of an epithelium; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including astrocyte fate commitment; negative regulation of photoreceptor cell differentiation; and positive regulation of macromolecule biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SOX8 (SRY-box transcription factor 8).
RGD Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including nervous system development; positive regulation of morphogenesis of an epithelium; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including astrocyte fate commitment; negative regulation of photoreceptor cell differentiation; and positive regulation of macromolecule biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SOX8 (SRY-box transcription factor 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45803
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
14.5850M14.5855M14.5860M14.5865M14.5870M14.5875M14.5880M14.5885M14.5890M14.5895M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions