Gene

Mppe1

Species
Rattus norvegicus
Symbol
Mppe1
Name
metallophosphoesterase 1
Synonyms
  • LOC361344
  • post-GPI attachment to proteins factor 5
Biotype
protein coding gene
Automated Description
Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Predicted to be involved in GPI anchor biosynthetic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in several cellular components, including cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human MPPE1 (metallophosphoesterase 1).
RGD Description
Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Predicted to be involved in GPI anchor biosynthetic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in several cellular components, including cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human MPPE1 (metallophosphoesterase 1); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13315
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
60.764M60.766M60.768M60.770M60.772M60.774M60.776M60.778M60.780M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions