Gene

Klf12

Species
Rattus norvegicus
Symbol
Klf12
Name
KLF transcription factor 12
Synonyms
  • Krueppel-like factor 12
  • Kruppel-like factor 12
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Orthologous to human KLF12 (KLF transcription factor 12).
RGD Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Orthologous to human KLF12 (KLF transcription factor 12); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23235
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
76.65M76.70M76.75M76.80M76.85M76.90M76.95M77.00M77.05M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions