Gene

Cers4

Species
Rattus norvegicus
Symbol
Cers4
Name
ceramide synthase 4
Synonyms
  • LAG1 homolog, ceramide synthase 4
  • LAG1 longevity assurance homolog 4
Biotype
protein coding gene
Automated Description
Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Orthologous to human CERS4 (ceramide synthase 4).
RGD Description
Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Orthologous to human CERS4 (ceramide synthase 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12560
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensCERS410 of 10YesYes  
Mus musculusCers49 of 9YesYes   
Danio reriocers4b5 of 9YesYes   
Danio reriocers4a4 of 9NoYes   
Drosophila melanogasterschlank4 of 9YesNo   
Caenorhabditis eleganshyl-27 of 9YesNo   
Saccharomyces cerevisiaeLAC17 of 9YesYes   
Saccharomyces cerevisiaeLAG17 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Cers2138963437 of 9 
Cers3239957407 of 9 
Cers6338759427 of 9 
Cers5441553387 of 9 
Cers1530847312 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051347.1:g.2857576C>Tvariant
SNP
  • intron variant
NC_051347.1:g.2853014A>Gvariant
SNP
  • intron variant
NC_051347.1:g.2861143G>Avariant
SNP
  • intron variant
NC_051347.1:g.2862014C>Avariant
SNP
  • intron variant
NC_051347.1:g.2862978C>Gvariant
SNP
  • intron variant
NC_051347.1:g.2855959G>Avariant
SNP
  • intron variant
NC_051347.1:g.2873229G>Tvariant
SNP
  • intron variant
NC_051347.1:g.2867759T>Cvariant
SNP
  • intron variant
NC_051347.1:g.2868837C>Tvariant
SNP
  • intron variant
NC_051347.1:g.2873043T>Cvariant
SNP
  • intron variant
Showing 1 - 10 of 209 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
2.855M2.860M2.865M2.870M2.875M2.880M2.885M2.890M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available