Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in establishment of animal organ orientation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human IRX4 (iroquois homeobox 4).
RGD Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in establishment of animal organ orientation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human IRX4 (iroquois homeobox 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,7-dihydropurine-6-thione.