Gene

Irx4

Species
Rattus norvegicus
Symbol
Irx4
Name
iroquois homeobox 4
Synonyms
  • Iroquois related homeobox 4
  • Iroquois related homeobox 4 (Drosophila)
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in establishment of animal organ orientation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human IRX4 (iroquois homeobox 4).
RGD Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in establishment of animal organ orientation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human IRX4 (iroquois homeobox 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,7-dihydropurine-6-thione.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11211
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
30.031M30.032M30.033M30.034M30.035M30.036M30.037M30.038M30.039M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions