Gene

Bcl6

Species
Rattus norvegicus
Symbol
Bcl6
Name
BCL6, transcription repressor
Synonyms
  • B-cell CLL/lymphoma 6
  • B-cell leukemia/lymphoma 6
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and transcription corepressor binding activity. Predicted to be involved in several processes, including positive regulation of regulatory T cell differentiation; regulation of gene expression; and type 2 immune response. Predicted to act upstream of or within several processes, including hemopoiesis; regulation of gene expression; and regulation of lymphocyte activation. Predicted to be located in Golgi apparatus; nuclear lumen; and replication fork. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor).
RGD Description
Predicted to enable several functions, including DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and transcription corepressor binding activity. Predicted to be involved in several processes, including positive regulation of regulatory T cell differentiation; regulation of gene expression; and type 2 immune response. Predicted to act upstream of or within several processes, including hemopoiesis; regulation of gene expression; and regulation of lymphocyte activation. Predicted to be located in Golgi apparatus; nuclear lumen; and replication fork. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor); PARTICIPATES IN interleukin-4 signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24394
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
76.856M76.858M76.860M76.862M76.864M76.866M76.868M76.870M76.872M76.874M76.876M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions