Predicted to enable several functions, including DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and transcription corepressor binding activity. Predicted to be involved in several processes, including positive regulation of regulatory T cell differentiation; regulation of gene expression; and type 2 immune response. Predicted to act upstream of or within several processes, including hemopoiesis; regulation of gene expression; and regulation of lymphocyte activation. Predicted to be located in Golgi apparatus; nuclear lumen; and replication fork. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor).
RGD Description
Predicted to enable several functions, including DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and transcription corepressor binding activity. Predicted to be involved in several processes, including positive regulation of regulatory T cell differentiation; regulation of gene expression; and type 2 immune response. Predicted to act upstream of or within several processes, including hemopoiesis; regulation of gene expression; and regulation of lymphocyte activation. Predicted to be located in Golgi apparatus; nuclear lumen; and replication fork. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in B-cell lymphoma and diffuse large B-cell lymphoma. Orthologous to human BCL6 (BCL6 transcription repressor); PARTICIPATES IN interleukin-4 signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.