Gene

Mrc1

Species
Rattus norvegicus
Symbol
Mrc1
Name
mannose receptor, C type 1
Synonyms
  • LOC291327
  • macrophage mannose receptor 1
Biotype
protein coding gene
Automated Description
Predicted to enable D-mannose binding activity; cargo receptor activity; and transmembrane signaling receptor activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to act upstream of or within cellular response to interleukin-4; cellular response to lipopolysaccharide; and cellular response to type II interferon. Predicted to be located in cell surface and endosome membrane. Predicted to be active in plasma membrane. Orthologous to human MRC1 (mannose receptor C-type 1).
RGD Description
Predicted to enable D-mannose binding activity; cargo receptor activity; and transmembrane signaling receptor activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to act upstream of or within cellular response to interleukin-4; cellular response to lipopolysaccharide; and cellular response to type II interferon. Predicted to be located in cell surface and endosome membrane. Predicted to be active in plasma membrane. Orthologous to human MRC1 (mannose receptor C-type 1); PARTICIPATES IN phagocytosis pathway; tuberculosis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22803
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
77.25M77.26M77.27M77.28M77.29M77.30M77.31M77.32M77.33M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions