Gene

Col8a1

Species
Rattus norvegicus
Symbol
Col8a1
Name
collagen type VIII alpha 1 chain
Synonyms
  • collagen alpha-1(VIII) chain
  • collagen, type VIII, alpha 1
Biotype
protein coding gene
Automated Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in endodermal cell differentiation and extracellular matrix organization. Predicted to act upstream of or within camera-type eye morphogenesis; endothelial cell proliferation; and positive regulation of cell-substrate adhesion. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human COL8A1 (collagen type VIII alpha 1 chain).
RGD Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in endodermal cell differentiation and extracellular matrix organization. Predicted to act upstream of or within camera-type eye morphogenesis; endothelial cell proliferation; and positive regulation of cell-substrate adhesion. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human COL8A1 (collagen type VIII alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15427
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
42.78M42.80M42.82M42.84M42.86M42.88M42.90M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions