Gene

Tubb2b

Species
Rattus norvegicus
Symbol
Tubb2b
Name
tubulin, beta 2B class IIb
Synonyms
  • beta-tubulin T beta15 (aa 1-445)
  • LOC291081
Biotype
protein coding gene
Automated Description
Predicted to enable GTP binding activity and protein heterodimerization activity. Predicted to be a structural constituent of cytoskeleton. Involved in neuron migration. Predicted to be located in intercellular bridge and mitotic spindle. Predicted to be active in Schaffer collateral - CA1 synapse; cytoplasm; and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb).
RGD Description
Predicted to enable GTP binding activity and protein heterodimerization activity. Predicted to be a structural constituent of cytoskeleton. Involved in neuron migration. Predicted to be located in intercellular bridge and mitotic spindle. Predicted to be active in Schaffer collateral - CA1 synapse; cytoplasm; and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11588
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
30.7480M30.7485M30.7490M30.7495M30.7500M30.7505M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions