Gene

Rig1

Species
Rattus norvegicus
Symbol
Rig1
Name
RNA sensor RIG-1
Synonyms
  • antiviral innate immune response receptor RIG-I
  • Ddx58
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including ATP hydrolysis activity; GTP binding activity; and nucleic acid binding activity. Predicted to be involved in several processes, including positive regulation of cytokine production; regulation of defense response; and response to virus. Predicted to act upstream of or within response to exogenous dsRNA. Predicted to be located in actin cytoskeleton; bicellular tight junction; and ruffle membrane. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm. Orthologous to human RIGI (RNA sensor RIG-I).
RGD Description
Predicted to enable several functions, including ATP hydrolysis activity; GTP binding activity; and nucleic acid binding activity. Predicted to be involved in several processes, including positive regulation of cytokine production; regulation of defense response; and response to virus. Predicted to act upstream of or within response to exogenous dsRNA. Predicted to be located in actin cytoskeleton; bicellular tight junction; and ruffle membrane. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm. Orthologous to human RIGI (RNA sensor RIG-I); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,3',4,4',5-pentachlorobiphenyl.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14074
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
55.325M55.330M55.335M55.340M55.345M55.350M55.355M55.360M55.365M55.370M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions