Predicted to enable DNA topoisomerase type I (single strand cut, ATP-independent) activity and RNA topoisomerase activity. Predicted to be involved in DNA recombination; DNA repair; and DNA topological change. Predicted to act upstream of or within chromosome segregation. Predicted to be located in condensed chromosome. Predicted to be part of DNA topoisomerase III-beta-TDRD3 complex. Predicted to be active in nucleus. Orthologous to human TOP3B (DNA topoisomerase III beta).
RGD Description
Predicted to enable DNA topoisomerase type I (single strand cut, ATP-independent) activity and RNA topoisomerase activity. Predicted to be involved in DNA recombination; DNA repair; and DNA topological change. Predicted to act upstream of or within chromosome segregation. Predicted to be located in condensed chromosome. Predicted to be part of DNA topoisomerase III-beta-TDRD3 complex. Predicted to be active in nucleus. Orthologous to human TOP3B (DNA topoisomerase III beta); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.