Gene

Rad17

Species
Rattus norvegicus
Symbol
Rad17
Name
RAD17 checkpoint clamp loader component
Synonyms
  • cell cycle checkpoint protein RAD17
  • LOC310034
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin binding activity and chromatin-protein adaptor activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in several processes, including mitotic DNA integrity checkpoint signaling; negative regulation of DNA replication; and protein localization to site of double-strand break. Predicted to act upstream of or within DNA damage response. Predicted to be located in chromosome, telomeric region; nucleolus; and nucleoplasm. Predicted to be part of Rad17 RFC-like complex. Predicted to be active in site of double-strand break. Orthologous to human RAD17 (RAD17 checkpoint clamp loader component).
RGD Description
Predicted to enable chromatin binding activity and chromatin-protein adaptor activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in several processes, including mitotic DNA integrity checkpoint signaling; negative regulation of DNA replication; and protein localization to site of double-strand break. Predicted to act upstream of or within DNA damage response. Predicted to be located in chromosome, telomeric region; nucleolus; and nucleoplasm. Predicted to be part of Rad17 RFC-like complex. Predicted to be active in site of double-strand break. Orthologous to human RAD17 (RAD17 checkpoint clamp loader component); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12172
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
31.765M31.770M31.775M31.780M31.785M31.790M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions