Gene

Tfeb

Species
Rattus norvegicus
Symbol
Tfeb
Name
transcription factor EB
Synonyms
  • LOC316214
  • MGC116240
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; defense response to bacterium; and positive regulation of metabolic process. Predicted to act upstream of or within lysosome organization and positive regulation of DNA-templated transcription. Predicted to be located in cytosol and lysosomal membrane. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human TFEB (transcription factor EB).
RGD Description
Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; defense response to bacterium; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within lysosome organization and positive regulation of DNA-templated transcription. Predicted to be located in cytosol and lysosomal membrane. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human TFEB (transcription factor EB); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45776
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
13.200M13.205M13.210M13.215M13.220M13.225M13.230M13.235M13.240M13.245M13.250M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions