Version: 8.0.0Date: Tue Jan 28 2025
Gene
Tent4b
- Species
- Rattus norvegicus
- Symbol
- Tent4b
- Name
- terminal nucleotidyltransferase 4B
- Synonyms
- LOC307745
- non-canonical poly(A) RNA polymerase PAPD5
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable guanylyltransferase activity; poly(A) RNA polymerase activity; and telomerase RNA binding activity. Predicted to be involved in RNA metabolic process; carbohydrate homeostasis; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in cytosol and plasma membrane. Predicted to be part of TRAMP complex. Predicted to be active in nucleolus. Orthologous to human TENT4B (terminal nucleotidyltransferase 4B).
- RGD Description
- Predicted to enable guanylyltransferase activity; poly(A) RNA polymerase activity; and telomerase RNA binding activity. Predicted to be involved in several processes, including RNA metabolic process; negative regulation of telomere maintenance via telomerase; and regulation of mRNA stability. Predicted to be located in cytosol and plasma membrane. Predicted to be part of TRAMP complex. Predicted to be active in nucleolus. Orthologous to human TENT4B (terminal nucleotidyltransferase 4B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR23092
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | TENT4B | 10 of 10 | Yes | Yes | ☑☑☑☑☑☑☑☑☑☑ |
| Mus musculus | Tent4b | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Xenopus tropicalis | tent4b | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Danio rerio | tent4b | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Drosophila melanogaster | Trf4-1 | 7 of 9 | Yes | Yes | ☑ ☑☐☐☑☑☑☑☑ |
| Drosophila melanogaster | Trf4-2 | 5 of 9 | No | Yes | ☑ ☐☑☐☑☐☑☑☐ |
| Caenorhabditis elegans | gld-4 | 6 of 9 | Yes | Yes | ☑ ☑☐☐☑☑☑☐☑ |
| Saccharomyces cerevisiae | PAP2 | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
| Saccharomyces cerevisiae | TRF5 | 7 of 9 | No | Yes | ☑ ☑☑☐☑☑☑☐☑ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Paralogy
| Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
|---|---|---|---|---|---|---|
| Tent4a | 1 | 809 | 56 | 47 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
Disease Associations
Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|---|
| No records match query. Try removing filters. | ||||||||
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Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- Chr19:18807525...18869537 - (62.01 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction