Gene

Sf3b4

Species
Rattus norvegicus
Symbol
Sf3b4
Name
splicing factor 3B subunit 4
Synonyms
  • LOC295270
Biotype
protein coding gene
Automated Description
Predicted to enable RNA binding activity and splicing factor binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex; U2 snRNP; and U2-type precatalytic spliceosome. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Nager acrofacial dysostosis; cervical cancer; and hepatocellular carcinoma. Orthologous to human SF3B4 (splicing factor 3b subunit 4).
RGD Description
Predicted to enable RNA binding activity and splicing factor binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within positive regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex; U2 snRNP; and U2-type precatalytic spliceosome. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Nager acrofacial dysostosis; cervical cancer; and hepatocellular carcinoma. Orthologous to human SF3B4 (splicing factor 3b subunit 4); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR48030
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
183.7330M183.7335M183.7340M183.7345M183.7350M183.7355M183.7360M183.7365M183.7370M183.7375M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions