Gene

Mvb12b

Species
Rattus norvegicus
Symbol
Mvb12b
Name
multivesicular body subunit 12B
Synonyms
  • Fam125b
  • family with sequence similarity 125, member B
Biotype
protein coding gene
Automated Description
Predicted to enable lipid binding activity. Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Predicted to be located in several cellular components, including cytosol; early endosome; and nucleus. Predicted to be part of ESCRT I complex. Predicted to be active in late endosome. Orthologous to human MVB12B (multivesicular body subunit 12B).
RGD Description
Predicted to enable lipid binding activity. Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Predicted to be located in several cellular components, including cytosol; early endosome; and nucleus. Predicted to be part of ESCRT I complex. Predicted to be active in late endosome. Orthologous to human MVB12B (multivesicular body subunit 12B); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR31547
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
17.04M17.06M17.08M17.10M17.12M17.14M17.16M17.18M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions