Gene

Ei24

Species
Rattus norvegicus
Symbol
Ei24
Name
EI24, autophagy associated transmembrane protein
Synonyms
  • etoposide induced 2.4
  • etoposide induced 2.4 mRNA
Biotype
protein coding gene
Automated Description
Predicted to enable importin-alpha family protein binding activity. Predicted to be involved in macroautophagy. Predicted to act upstream of or within several processes, including cellular response to UV-C; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of protein import into nucleus. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in endoplasmic reticulum. Orthologous to human EI24 (EI24 autophagy associated transmembrane protein).
RGD Description
Predicted to enable importin-alpha family protein binding activity. Predicted to be involved in macroautophagy. Predicted to act upstream of or within several processes, including cellular response to UV-C; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of protein import into nucleus. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in endoplasmic reticulum. Orthologous to human EI24 (EI24 autophagy associated transmembrane protein); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,3-dinitrobenzene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21389
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            36.496M36.498M36.500M36.502M36.504M36.506M36.508M36.510M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Ei24 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
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              Genetic Interactions

              Ei24 role
              Ei24 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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