Version: 8.0.0
Date: Tue Jan 28 2025
Rad23a
Rattus norvegicusRGD:1309899
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Rad23a

Species
Rattus norvegicus
Symbol
Rad23a
Name
RAD23 homolog A, nucleotide excision repair protein
Synonyms
  • LOC361381
  • RAD23 homolog A
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including enzyme binding activity; proteasome binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of viral genome replication; and protein destabilization. Predicted to act upstream of or within DNA damage response. Predicted to be located in Golgi apparatus and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human RAD23A (RAD23 homolog A, nucleotide excision repair protein).
RGD Description
Predicted to enable several functions, including enzyme binding activity; proteasome binding activity; and ubiquitin binding activity. Predicted to be involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of viral genome replication; and protein destabilization. Predicted to act upstream of or within DNA damage response. Predicted to be located in Golgi apparatus and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleoplasm. Orthologous to human RAD23A (RAD23 homolog A, nucleotide excision repair protein); PARTICIPATES IN nucleotide excision repair pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10621
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Rad23a molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Rad23a role
            Rad23a genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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