Gene

Trim27

Species
Rattus norvegicus
Symbol
Trim27
Name
tripartite motif-containing 27
Synonyms
  • LOC291171
  • MGC189472
Biotype
protein coding gene
Automated Description
Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including defense response to symbiont; negative regulation of metabolic process; and regulation of gene expression. Predicted to act upstream of or within negative regulation of gene expression, epigenetic and positive regulation of actin nucleation. Predicted to be located in endosome and nucleus. Predicted to be part of retromer complex. Predicted to be active in cytoplasm. Orthologous to human TRIM27 (tripartite motif containing 27).
RGD Description
Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including Arp2/3 complex-mediated actin nucleation; defense response to symbiont; and regulation of gene expression. Predicted to act upstream of or within negative regulation of gene expression, epigenetic and positive regulation of actin nucleation. Predicted to be located in endosome and nucleus. Predicted to be part of retromer complex. Predicted to be active in cytoplasm. Orthologous to human TRIM27 (tripartite motif containing 27); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24103
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            43.540M43.542M43.544M43.546M43.548M43.550M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Trim27 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
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              Genetic Interactions

              Trim27 role
              Trim27 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
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