Gene

Prepl

Species
Rattus norvegicus
Symbol
Prepl
Name
prolyl endopeptidase-like
Synonyms
  • LOC298771
  • MGC105586
Biotype
protein coding gene
Automated Description
Predicted to enable peptidase activity. Predicted to be involved in Golgi to plasma membrane protein transport; regulation of synaptic vesicle exocytosis; and retrograde transport, endosome to Golgi. Predicted to be located in mitochondrion and trans-Golgi network. Predicted to be active in Golgi apparatus and cytoskeleton. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 22. Orthologous to human PREPL (prolyl endopeptidase like).
RGD Description
Predicted to enable peptidase activity. Predicted to be involved in Golgi to plasma membrane protein transport; regulation of synaptic vesicle exocytosis; and retrograde transport, endosome to Golgi. Predicted to be located in mitochondrion and trans-Golgi network. Predicted to be active in Golgi apparatus and cytoskeleton. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 22. Orthologous to human PREPL (prolyl endopeptidase like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11757
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
9.585M9.590M9.595M9.600M9.605M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions