Gene

Dnaaf2

Species
Rattus norvegicus
Symbol
Dnaaf2
Name
dynein, axonemal, assembly factor 2
Synonyms
  • dynein assembly factor 2, axonemal
  • Ktu
Biotype
protein coding gene
Automated Description
Predicted to be involved in axonemal dynein complex assembly; cilium-dependent cell motility; and epithelial cilium movement involved in extracellular fluid movement. Predicted to act upstream of or within several processes, including axonemal dynein complex assembly; establishment of left/right asymmetry; and response to retinoic acid. Predicted to be located in cytosol and dynein axonemal particle. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 10. Orthologous to human DNAAF2 (dynein axonemal assembly factor 2).
RGD Description
Predicted to be involved in axonemal dynein complex assembly; cilium-dependent cell motility; and epithelial cilium movement involved in extracellular fluid movement. Predicted to act upstream of or within several processes, including axonemal dynein complex assembly; establishment of left/right asymmetry; and response to retinoic acid. Predicted to be located in cytosol and dynein axonemal particle. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 10. Orthologous to human DNAAF2 (dynein axonemal assembly factor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22997
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Pih1d2134639203 of 9 
Pih1d1236835193 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
87.661M87.662M87.663M87.664M87.665M87.666M87.667M87.668M87.669M87.670MENSRNOT00000059187.5 (Dnaaf2)NM_001014197.4 (Dnaaf2)ENSRNOT00000103459.1 (ENSRNOG00000066119)ENSRNOT00000005835.6 (Pole2)ENSRNOT00000104479.1 (Pole2)NM_001169108.1 (Pole2)XM_006240154.5 (Pole2)XM_039111983.2 (Pole2)XM_039111988.2 (Pole2)ENSRNOT00000064668.3 (Klhdc1)Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions