Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including positive regulation of macromolecule biosynthetic process; response to peptidoglycan; and response to virus. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Biomarker of obstructive jaundice and ureteral obstruction. Human ortholog(s) of this gene implicated in herpes simplex; inflammatory bowel disease 14; multiple sclerosis; rheumatoid arthritis; and systemic lupus erythematosus. Orthologous to human IRF5 (interferon regulatory factor 5).
RGD Description
Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including positive regulation of macromolecule biosynthetic process; response to peptidoglycan; and response to virus. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Biomarker of obstructive jaundice and ureteral obstruction. Human ortholog(s) of this gene implicated in herpes simplex; inflammatory bowel disease 14; multiple sclerosis; rheumatoid arthritis; and systemic lupus erythematosus. Orthologous to human IRF5 (interferon regulatory factor 5); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene.