Gene

Plekhf1

Species
Rattus norvegicus
Symbol
Plekhf1
Name
pleckstrin homology and FYVE domain containing 1
Synonyms
  • LOC308543
  • PH domain-containing family F member 1
Biotype
protein coding gene
Automated Description
Predicted to enable phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in several processes, including endosome to lysosome transport; positive regulation of intrinsic apoptotic signaling pathway; and protein localization to plasma membrane. Predicted to be located in endosome. Predicted to be active in early endosome and lysosome. Orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1).
RGD Description
Predicted to enable phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in several processes, including endosome to lysosome transport; positive regulation of intrinsic apoptotic signaling pathway; and protein localization to plasma membrane. Predicted to be located in endosome. Predicted to be active in early endosome and lysosome. Orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46280
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
90.905M90.906M90.907M90.908M90.909M90.910M90.911M90.912M90.913M90.914M90.915M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions