Gene

Cbfa2t3

Species
Rattus norvegicus
Symbol
Cbfa2t3
Name
CBFA2/RUNX1 partner transcriptional co-repressor 3
Synonyms
  • CBFA2/RUNX1 translocation partner 3
  • core-binding factor, runt domain, alpha subunit 2
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin binding activity and transcription corepressor activity. Predicted to be involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of generation of precursor metabolites and energy; and response to hypoxia. Predicted to act upstream of or within granulocyte differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human CBFA2T3 (CBFA2/RUNX1 partner transcriptional co-repressor 3).
RGD Description
Predicted to enable chromatin binding activity and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of DNA-templated transcription; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of generation of precursor metabolites and energy. Predicted to act upstream of or within granulocyte differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human CBFA2T3 (CBFA2/RUNX1 partner transcriptional co-repressor 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10379
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
50.68M50.69M50.70M50.71M50.72M50.73M50.74M50.75M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions